成分股Caribou Biosciences跌22.2%表现最差,Aurinia Pharmaceuticals跌17.3%, Arcturus Therapeutics Holdings Inc.和Design Therapeutics至少跌超16.3%,Crispr Therapeutics、Lyell Immunopharma、Sesen Bio、 ObsEva、Tonix Pharmaceuticals Holding、Beam、Olema至少跌超14.0%,诺瓦瓦克斯医药(NVAX)也跌13.7%,Altimmune涨超7.0%,OptiNose涨超24.3%,bluebird bio涨超26.0%,Day One Biopharmaceuticals涨超105.4%。