成分股Pacific Biosciences of California(PACB)收跌50.62%,该公司估计全年营收1.7亿-2.0亿美元,分析师预期2.387亿美元,无法实现2026年收入至少5亿美元的业绩指引。莱斯康制药(LXRX)跌9.36%,Vera Therapeutics跌8.51%,Wave Life Sciences也跌8.36%;Day One Biopharmaceuticals则收涨5.49%,Avadel Pharmaceuticals Plc.涨6.41%,Humacyte涨6.62%,Alx Oncology Holdings涨12.41%,Intra-Cellular Therapies也涨23.29%。