成分股uniQure NV收跌27.75%,Lexeo Therapeutics跌26.97%,Sarepta Therapeutics跌26.56%跌幅第三大,Replimune、CG Oncology、Larimar Therapeutics Inc.、Syndax Pharmaceuticals、Xencor、Allogene Therapeutics、Solid Biosciences、Rocket Pharma跌25.17%-19.62%紧随其后。神经分泌生物科学则收涨8.36%表现第二,CorMedix涨23.59%。